New First-in-class Treatment Fycompa® Launches in Norway for Most Common Form of Epilepsy (y 2)

        
        - Zonegran(R) (zonisamide) as monotherapy and adjunctive therapy in adult
          patients with partial-onset seizures, with or without secondary generalisation.
          (Zonegran is under license from the originator Dainippon Sumitomo Pharma)
        - Zebinix(R) (eslicarbazepine acetate) as adjunctive therapy in adult patients
          with partial-onset seizures, with or without secondary generalisation. (Zebinix is
          under license from BIAL)
        - Inovelon(R) (rufinamide) for the adjunctive treatment of seizures associated
          with Lennox-Gastaut Syndrome in patients >4 years
        - Fycompa(R) (perampanel) for use as an adjunctive treatment for partial onset
          seizures, with or without secondarily generalised seizures, in patients with epilepsy
          aged 12 years and older

About Eisai

Eisai recently expanded their UK Hatfield commercial, research and manufacturing facility which now supports the company's growing EMEA business.

Eisai concentrates its R&D activities in three key areas:

        
        - Neuroscience, including: Alzheimer's disease, multiple sclerosis,
          neuropathic pain, epilepsy, depression
        - Oncology including: anticancer therapies; tumour regression, tumour
          suppression, antibodies, etc and supportive cancer therapies; pain relief, nausea
        - Vascular/Immunological reaction including: acute coronary syndrome,
          atherothrombotic disease, rheumatoid arthritis, psoriasis, Crohn's disease

With operations in the U.S., Asia, Europe and its domestic home market of Japan, Eisai employs more than 11,000 people worldwide. In Europe, Eisai undertakes sales and marketing operations in over 20 markets, including the United Kingdom, France, Germany, Italy, Spain, Switzerland, Sweden, Ireland, Austria, Denmark, Finland, Norway, Portugal, Iceland, Czech Republic, Slovakia, the Netherlands, Belgium, Luxembourg, the Middle East and Russia.

For further information please visit our web site http://www.eisai.com.

References

1. Fycompa. Summary of Product Characteristics. August 2012

2. http://www.rightdiagnosis.com/e/epilepsy/stats-country.htm (last accessed Nov 2012)

3. French JA. Refractory Epilepsy; Clinical Overview. Epilepsia 2007: 48 (Suppl1) 3 - 7

4. Rogawski MA. Epilepsy Currents 2011;11:56-63.

5. Krauss GM. Serratosa JM, Villanueva V et al. Neurology 2012: http://www.neurology.org [Accessed August 2012].

6. French JA. Neurology 2012;79:589-596.

7. French JA et al. (305) Epilepsia 2012:1-9. In press online.

8. Ben-Menachem E,Krauss GL, Noachtar S et al. Abstract presented at ECE 2012

9. Steinhoff BJ, Gauffin H, McKee P et al. Abstract presented at ECE 2012

10. Trinka E, Straub H, Squillacote D et al. Abstract presented at ECE 2012

11. Epilepsy in the WHO European Region: Fostering Epilepsy Care in Europe. http://www.ibe-epilepsy.org/downloads/EURO%20Report%20160510... [Accessed August 2012].

12. Pugliatti M, et al. Epilepsia 2007: 48(12) 2224 - 2233.

Date of preparation: January 2013

Job code: Perampanel-EU0026

CONTACT: Media Enquiries: Eisai Europe Ltd, Cressida Robson / CharlotteAndrews, +44(0)7908-314-155/ +44(0)7947-231-513, Cressida_Robson@eisai.net,Charlotte_andrews@eisai.net; Tonic Life Communications, Benjamyn Tan/HollieMatthews, +44(0)207-798-9262 / +44(0)207-7798-9992,hollie.matthews@toniclc.com, eisaiepilepsy@toniclc.com