Halaven® (Eribulin) Demonstrates Overall Survival Benefit in Rare Soft Tissue Sarcoma Sub-types (y 3)

Actualizado 08/11/2016 12:58:55 CET

1) Schöffski P, et al. Randomized, open-label, multicenter, phase 3 study of eribulin

versus dacarbazine in patients (pts) with leiomyosarcoma (LMS) and adipocytic sarcoma

(ADI). DGHO 2015; Abstract 258

2) Twelves C, et al. Efficacy and safety of eribulin in combination with capecitabine in

patients with metastatic breast cancer: an open-label phase II dose-confirmation

study. DGHO 2015; Abstract presented at DGHO 2015

3) Dobbie M, Long lasting disease stabilisation with Eribulin. DGHO 2015; Abstract

presented at DGHO 2015

4) SPC Halaven (updated June 2014). Available at:

http://www.medicines.org.uk/emc/medicine/24382/SPC/Halaven+0.44+mg+ml+solution+for+injection

 Accessed: September 2015

5) Motzer R, Randomized phase 2 three-arm trial of lenvatinib (LEN), everolimus (EVE),

and LEN _ EVE in patients with metastatic renal cell carcinmoa (mRCC). DGHO 2015;

Abstract presented at DGHO 2015

6) Elisei R, et al. Subgroup Analysis According to Differentiated Thyroid Cancer

Histology in Phase 3 (SELECT) Trial of Lenvatinib. DGHO 2015; Abstract presented at

DGHO 2015

7) SPC Lenvima (updated May 2015). Available at:

http://www.medicines.org.uk/emc/medicine/30412  Accessed: September 2015

8) Macmillan. What are soft tissue sarcomas? Available at:

http://www.macmillan.org.uk/Cancerinformation/Cancertypes/Softtissuesarcomas/Aboutsofttissuesarcomas/Softtissuesarcomas.aspx

 Accessed: September 2015

9) National Cancer Institute.

http://www.cancer.gov/cancertopics/pdq/treatment/adult-soft-tissue-sarcoma/HealthProfessional/page1

 Accessed: September 2015

10) Cancer Research UK, Soft Tissue Sarcoma Incidence Statistics:

http://www.cancerresearchuk.org/cancer-info/cancerstats/types/soft-tissue-sarcoma/incidence

 Accessed: September 2015

11) ESMO Guidance:

http://annonc.oxfordjournals.org/content/25/suppl_3/iii102.full.pdf+html Accessed:

July 2015

12) M. Schuichi, et al. Soft-Tissue Sarcoma Surveillance Counterpoint: Japan. Current

Clinical Oncology. 2013; 233-234

13) H. Tsujii, et al. Carbon-Ion Radiotherapy: Principles, Practices, and Treatment

Planning. Springer. 2014; (XII)312:237

14) Fletcher et al. World Health Organization Classification of Tumours of Soft Tissue and

Bone (4th Edition). Lyon: IARC Press, 2013.

15) Okamoto K, et al. Distinct Binding Mode of Multikinase Inhibitor Lenvatinib Revealed

by Biochemical Characterization. ACS Med. Chem. Lett 2015; 6:89-94

16) Wu P et al. Small-molecule kinase inhibitors: an analysis of FDA-approved drugs. Drug

Discovery Today 2015; 1-6

17) Schlumberger M, et al. Relationship Between Thyroid-Stimulating Hormone Levels and

Outcomes from the Randomized, Double-Blind, Phase 3 Study of (E7080) Lenvatinib in

Differentiated Cancer of the Thyroid (SELECT). Available at:

https://endo.confex.com/endo/2015endo/webprogram/Paper20459.html Accessed:

September 2015

18) Brito J et al. BMJ 2013; 347

19) Cabanillas ME, Dadu R. Optimizing therapy for radioactive iodine-refractory

differentiated thyroid cancer : Current state of the art and future directions.

Minerva Endocrinol. 2012 Dec; 37(4):335-356.

20) EUCAN 2015. http://eu-cancer.iarc.fr/EUCAN/Cancer.aspx?Cancer=35  Accessed: June

2015

21) Thyroid Cancer Basics. 2011. Available at: http://www.thyca.org  Accessed: June

2015

22) Pacini F et al. ESMO Guidelines Working Group. Ann Oncol. 2012;23 (suppl 7)

:vii110-vii119.

 

 

Date of preparation: October 2015 

Oncology-UK0054 

 

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