In Japan, mogamulizumab has received approval for: relapsed or refractory CCR4-positive ATL in March 2012; relapsed or refractory CCR4-positive PTCL and relapsed or refractory CCR4-positive CTCL in March 2014; chemotherapy-native CCR4-positive ATL in December 2014; and, relapsed or refractory CTCL (CCR4-positive removed) in August 2018.
About Kyowa Kirin
Kyowa Hakko Kirin Co., Ltd. is a research-based life sciences company, with special strengths in biotechnologies. In the core therapeutic areas of oncology, nephrology and immunology/allergy, Kyowa Hakko Kirin leverages leading-edge biotechnologies centered on antibody technologies, to continually discover innovative new drugs and to develop and market those drugs world-wide. In this way, the company is working to realise its vision of becoming a Japan-based global specialty pharmaceutical company that contributes to the health and wellbeing of people around the world.
Kyowa Kirin International PLC is a wholly owned subsidiary of Kyowa Hakko Kirin and is a rapidly growing specialty pharmaceutical company engaged in the development and commercialisation of prescription medicines for the treatment of unmet therapeutic needs in Europe and the United States. Kyowa Kirin International is headquartered in Scotland.
You can learn more about the business at: http://www.kyowa-kirin.com
1. Leukemia & Lymphoma Society. Cutaneous T-Cell Lymphoma Facts. http://www.lls.org/sites/default/files/file_assets/FS5_Cutan... . Accessed May 2, 2018
2. Pierluigi Porcu et al. Quality of Life in Cutaneous T Cell Lymphoma Subjects Treated with the Anti-CCR4 Monoclonal Antibody Mogamulizumab Versus Vorinostat: Results from MAVORIC. Data presented at ASCO and EHA, and oral presentation at EORTC, 2018
3. Youn H Kim et al. Mogamulizumab versus vorinostat in previously treated cutaneous T-cell lymphoma (MAVORIC): an international, open-label, randomised, controlled phase 3 trial. Lancet Oncology 2018. Sep;19(9):1192-1204
4. Long-term complete remission induced by mogamulizumab in a severe Sezary patient, together with five different possible autoimmune manifestations [Abstract #059; Case study poster (external)]
CONTACT: Contact Kyowa Hakko Kirin Co. Ltd., Media, Hiroki Nakamura,+81-3-5205-7205, Email: firstname.lastname@example.org, Debbie Johnston, SprengThomson Ltd. (For Kyowa Kirin International PLC), 28 Sep. (0) - 141-548-5191,Mobile: +44(0)532-183811, Email: email@example.com, Yvette Venable,Kyowa Kirin International PLC, +44-7388-222-769, Email:Yvette.Venable@kyowakirin.com